Dystonic reactions to phenothiazine derivatives.
نویسندگان
چکیده
منابع مشابه
Dystonic reactions to phenothiazine derivatives.
Phenothiazine derivatives are widely used and their toxic effects in adults are well recognized. They include dizziness, mild skin reactions, jaundice, motor restlessness, and occasionally neuromuscular reactions. Dystonia and symptoms resembling parkinsonism usually occur only at high dosages. These are well-recognized complications in mental hospitals when drugs are being used to treat psycho...
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METOCLOPRAMIDE has been used in the treatment of various gastro-intestinal disorders for over a decade. Dystonic reactions to metoclopramide have been reported previously by Casteels-Van Daele et al (1970) and also Witzel (1968). The symptoms of dystonia appeared in their patients following the administration of metoclopramide in doses exceeding 0.5 mg/kg body weight for longer than a 24-hour p...
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THE benefits to both patient and surgeon followed until either their discharge home, conferred by the use of phenothiazine derivatives in anaesthesia are so great that a report on the routine use of these drugs with pethidine as a sole or main anaesthetic agent for adults in general, uroor to a convalescent or other hospital, or until the end of the third week after operation. The types of oper...
متن کاملOptical and electrochemical properties of ethynylaniline derivatives of phenothiazine, phenothiazine-5-oxide and phenothiazine-5,5-dioxide.
Three phenothiazine (PTZ) derivatives with varying degrees of sulfur oxidation states were synthesized as strong electron donors. The thioether, sulfoxide and sulfone PTZ-derivatives exhibited irreversible oxidation at 0.19 V, 0.29 V and 0.31 V versus ferrocene, respectively. Each PTZ derivative was emissive with lifetimes of 1.7 ns, 0.5 ns, and 0.5 ns and absolute quantum yields of 0.32, 0.23 ...
متن کاملNovel antipsychotics and acute dystonic reactions.
The growing use of atypical antipsychotics has led to a decrease of acute dystonic reactions (ADR). To evaluate the prevalence of ADR, we recorded all ADR occurring in a population of patients consecutively admitted to a psychiatric intensive care unit. Among 1337 cases treated with antipsychotics, we observed 41 cases (3.1%) affected by ADR. At discharge, mean chlorpromazine-equivalent daily d...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1966
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.41.219.551